---
gene_symbols:
  - EIN2
  - Skl1
gene_symbol_long: Ethylene Insensitive 2
gene_model_pub_name: Medtr7g101410
gene_model_full_id: medtr.A17.gnm5.ann1_6.MtrunA17Chr7g0264231
confidence: 5
curators:
  - Steven Cannon
phenotype_synopsis: Absence of discrete nodules, increased persistant rhizobila infection, radial swelling of primary infection zone, larger cotyledons, reduced apical hook angle, reduced develoment of ectopic root hairs, no loss of geotropism,and a lack of inhibition of both hypocotyl and root growth.  Reduced inhibition of root growth in response to application of exogenous cytokinin benzyl adenine.  Increased primary mycorrhizal infections by Glomus versiforme and Glomus intraradices.  Increased susceptability to damage caused by infection with R. solani necrotrophic fungus and P. medicaginis necrotrophic oomycete as well as larger numbers of P. medicaginis reproductive structures.  Reduced biphasic ethylene production after inoculation with P. medicaginis, reduced gene expression for one isoform of ACC oxidase transcripts, and reduced responsiveness of ethylene levels to exogenous ACC (all indicators of impaired autocatalytic ethylene production).
traits:
  - entity_name: gravity response trait
    entity: TO:0002693
  - entity_name: root hair length
    entity: TO:0002665
  - entity_name: root nodule number
    entity: TO:0000900
  - entity_name: hypocotyl morphology trait
    entity: TO:0000757
  - entity_name: seedling cotyledon size
    entity: TO:0000752
  - entity_name: root development trait
    entity: TO:0000656
  - entity_name: root system
    entity: PO:0025025
  - entity_name: hypocotyl
    entity: PO:0020100
  - entity_name: cotyledon
    entity: PO:0020030
  - entity_name: root
    entity: PO:0009005
  - entity_name: non-hair root epidermal cell
    entity: PO:0000263
  - entity_name: apical hook
    entity: PO:0000012
references:
  - citation: Weller, Foo et al., 2015
    doi: 10.1104/pp.15.00164
    pmid: 25792252
  - citation: Oellrich, Walls et al., 2015
    doi: 10.1186/s13007-015-0053-y
    pmid: 25774204