--- scientific_name: Glycine soja gene_symbols: - GsERD15B gene_symbol_long: Early Responsive to Dehydration 15B gene_model_pub_name: XP_028191281.1 gene_model_full_id: glyso.PI483463.gnm1.ann1.GlysoPI483463.11G164100 confidence: 4 curators: - Greg Murrell - Steven Cannon - Scott Kalberer comments: - A seven-base pair deletion in the GsERD15B promoter was discovered in the majority (42) of the 48 wild Glycine soja accessions with enhanced salt tolerance. - Increased expression of GsERD15B in response to salt stress was associated with up-regulation of two GmPAB genes (GmPAB-14G and GmPAB-17G) and known stress-related genes including ABA-related genes (GmABI1, GmABI2, GmbZIP1), a proline synthesis-related gene (GmP5CS), a catalase peroxidase gene (GmCAT4), water loss-related genes (GmPIP1:6, GmMYB84), and an ion exchanger encoding gene (GmSOS1). - GsERD15B overexpression enhanced the promoter activities of GmABI2, GmP5CS and GmbZIP1 in tobacco leaf assays. - GsERD15B encodes an ERD15 protein with transcriptional activation function. The ERD15 contains a conserved PAM2 domain in the N-terminus that mediates its interaction with the PABC domain of poly(A)-binding (PAB) proteins. phenotype_summary: Gene overexpression in Glycine enhanced salt tolerance probably by increasing the expression levels of genes related to ABA-signalling, proline content, catalase peroxidase, dehydration response and cation transport. traits: - entity_name: salt tolerance entity: TO:0006001 - relation_name: positively regulates relation: RO:0002213 references: - citation: Jin, Sun et al., 2021 doi: 10.1111/pbi.13536 pmid: 33368860